PHF6 single gene test
Methodology
Molecular
Test Description and clinical significance
Genes
PHF6
Disease:
Acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), skin cancer, lung adenocarcinoma, myelodysplastic neoplasm (MDS), endometrial endometrioid adenocarcinoma, colon adenocarcinoma, Borjeson-Forssman-Lehmann syndrome, and Lateral Meningocele Syndrome.
Next generation sequencing of gene panel. This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus.
Specimen Requirements
Collection:
At least 0.5 ml EDTA, citrate (ACD) or Heparinized whole blood or bone marrow aspirates for DNA mutations
Stability:
96hours/4 to 7 days refrigerated
Unacceptable Conditions:
Specimen submitted is in the incorrect fixative or anticoagulant. Specimen received after the stability date. Gross hemolysis. Frozen specimen. Insufficient specimen. Unlabeled. Left un-refrigerated for an extended period.
Storage & Transport
Blood, bone marrow specimens should be kept at room temperature and preferably received within 96 hrs of drawing. Samples that are 4 to 7 days old should be refrigerated.
CPT(s)
81479
New York Approved
NO
TAT
10 Days
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
