CARD11 single gene test
Methodology
Molecular
Test Description and clinical significance
Genes
CARD11 (exons 2-8)
Disease:
B cell lymphoproleferative disorders, B cell expansion, primary immunodeficiency, intestinal cancer, skin cancer, and stomach cancer, lung adenocarcinoma, colon adenocarcinoma, cutaneous melanoma, breast invasive ductal carcinoma, and endometrial endometrioid adenocarcinoma
Deep next generation sequencing of gene panel. Caspase recruitment domain family, member 11 (CARD11) is a gene that encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The protein functions in the regulation of the assembly of multiprotein complexes of the plasma membrane.
Specimen Requirements
Collection:
Specimen should contain atleast 0.5 mL of EDTA, citrate (ACD) or Heparinized bone marrow and peripheral blood specimens
Stability:
96hours/4 to 7 days refrigerated
Unacceptable Conditions:
Specimen submitted is in the incorrect fixative or anticoagulant.Specimen received after the stability date. Gross hemolysis. Frozen specimen. Insufficient specimen. Unlabeled. Left un-refrigerated for an extended period.
Storage & Transport
Blood specimens should be kept at room temperature and preferably received within 96 hours of drawing. Samples that are 4 to 7 days old should be refrigerated
CPT(s)
81479
New York Approved
NO
TAT
7 Days
*The CPT codes provided are for informational purposes only and are based on AMA guidelines The billing party is solely responsible for correct CPT coding.
